language

Product

Home page

Heparinase II（derived from Flavobacterium heparinum）

Bacterial heparinase II, also known as heparin lyase II, is a enzyme cloned from Flavobacterium heparinum and expressed in E. coli.

Email:

Phone:

Category:

Keywords:

Functional food

Pharmaceutical intermediate

Animal Nutrition

CDMO

产品详情

Product Information
Bacterial heparinase II, also known as heparin lyase II, is a enzyme cloned from Flavobacterium heparinum and expressed in E. coli. Heparinase II can degrade heparin and dermatan sulfate, making it a powerful tool for heparin structure research, clinical diagnostics, and industrial quality control.
Heparinase II cleaves heparan sulfate at the α(1→4) linkages between hexosamine and uronic acid residues (glucuronic acid and iduronic acid), and can also mediate controlled depolymerization of heparin, primarily yielding disaccharides. This reaction produces oligosaccharide products containing unsaturated uronic acids—mainly disaccharides—which can be detected by UV spectroscopy at 232 nm.
Product Applications
Heparinase II can be used to degrade heparin for structural analysis, such as determining the 1,6‑ring‑closure rate of enoxaparin sodium and analyzing the disaccharide profile of heparin sodium; it is also employed in combination with heparinase I and heparinase III to prepare low‑molecular‑weight heparin (LMWH); it degrades crude heparin to enable source‑identification via qPCR; and it degrades heparin and dermatan sulfate to produce heparin disaccharides and heparin oligosaccharides.

Online Consultation

If you have any questions, please leave us a message—we’ll be happy to assist you.

Submit

Recommended Products

Shark single-domain antibody

By innovatively reengineering biological scaffolds, the single-domain antibody products developed from shark-derived natural heavy-chain antibodies offer several advantages over conventional antibodies, including smaller molecular size, enhanced stability, superior tissue penetration, and reduced immunogenicity. These products are applicable in areas such as targeted drug development, in vitro diagnostic reagent design, and biopharmaceutical research, while also providing customized development and large-scale production services. This product can be tailored to generate single-domain antibodies with diverse antigen specificities, supporting end-to-end services from antibody screening through to large-scale purification. The resulting antibodies meet biopharmaceutical R&D and manufacturing‑grade purity standards, and corresponding quality‑control reports are available. Currently, we have established a mature platform for shark immunization, phage‑display library construction, and screening, enabling rapid generation of high‑affinity, highly specific single-domain antibody clones against a wide range of target antigens. We can flexibly adjust development timelines to align with clients’ project schedules, ensuring efficient delivery.

Intestinal peptide

Derived from the intestinal mucosa of healthy animals and prepared using bioenzymatic hydrolysis, it is rich in intestinal mucosal repair peptides and a variety of prebiotic factors.

Thymosin

Using thymic tissue from healthy animals as the raw material, high‑activity thymic immunopeptides are extracted through enzymatic hydrolysis and chromatographic purification.

Spleen peptide

Healthy animal spleens were used as the raw material, and immune-active peptides and multiple immunomodulatory factors were extracted via low-temperature enzymatic hydrolysis and ultrafiltration, thereby preserving their bioactivity.

Brain peptide

Derived from the brain tissue of healthy animals and purified using modern bioseparation techniques, a highly pure brain-derived neuroactive peptide has been obtained.

Liver peptide

Made from fresh, healthy animal liver and extracted using ultra‑low‑temperature extraction and enzymatic hydrolysis, this product preserves the liver’s unique bioactive peptides and nutritional factors.

Blood peptide

Using blood from healthy animals as the raw material, the product is purified through low-temperature enzymatic hydrolysis and membrane separation, removing impurities while preserving highly active heme peptides and a variety of bioactive nutrients.

Albumin peptide (egg white)

Using high-quality egg white as the core raw material, it is extracted through targeted enzymatic hydrolysis, preserving the natural nutritional bioactive components of egg white.

Committed to providing high-quality bioactive solutions for human health, animal nutrition, and agricultural biotechnology.

Shaoxing Jawin Biotechnology Co., Ltd.

Phone:0575-82161872

Email:info@jawinbio.com

Address: 3rd Floor, Building 3, No. 36 Kangyang Avenue, Hangzhou Bay Economic and Technological Development Zone, Shangyu District, Shaoxing City, Zhejiang Province

Website Development: China Enterprise Dynamics, Shaoxing

Telephone：0575-82161872

Email box：info@jawinbio.com

Sorry, there is currently no content in this section.

You can view other sections.

Business license

Business License